“Epstein-Barr Virus: A Novel Dimension in Cancer Development” dentro del libro Pathogens Associated with the Development of Cancer in Humans, de la Editorial Springer Nature
Noé Velázquez-Márquez, Genaro Alberto Paredes-Juárez, Verónica Vallejo-Ruiz El virus de Epstein-Barr: una nueva dimensión en el desarrollo del cáncer El virus de Epstein-Barr (VEB) es un herpesvirus gamma ubicuo vinculado a varios tipos de cáncer. Este capítulo profundiza en el potencial oncogénico del VEB, aprovechando los conocimientos genómicos y multiómicos recientes. A pesar de su presencia […]
Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer
Karla Rubio1,2,3,4, Addi J. Romero-Olmedo2,5, Pouya Sarvari6, Guruprasadh Swaminathan1, Vikas P. Ranvir7, Diana G. Rogel-Ayala1,2, Julio Cordero8,9, Stefan Günther10,11, Aditi Mehta2,12, Birgit Bassaly13, Peter Braubach14,15, Malgorzata Wygrecka16,17, Stefan Gattenlöhner13, Achim Tresch18,19,20, Thomas Braun11, Gergana Dobreva8,9, Miguel N. Rivera3,21, Indrabahadur Singh7, Johannes Graumann22,23, Guillermo Barreto1,2,4? Abstract: Background: Small cell lung cancer (SCLC) is an extremely aggressive […]
Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score.
Karla Rubio1,2,3,4,5,6 · Jason M. Müller7,8 · Aditi Mehta4,9,10 · Iris Watermann4,11 · Till Olchers4,11 · Ina Koch4,10,12 · Sabine Wessels4,13,14 · Marc A. Schneider4,13,14 · Tania Araujo?Ramos15 · Indrabahadur Singh15 · Christian Kugler4,11 · Mircea Gabriel Stoleriu4,10,12 · Mark Kriegsmann4,14,16 · Martin Eichhorn4,14,17 · Thomas Muley4,13,14 · Olivia M. Merkel4,9,10 · Thomas Braun3,18 · […]
EP300 as a Molecular Integrator of Fibrotic Transcriptional Programs
Karla Rubio, Alejandro Molina-Herrera, Andrea Pérez-González,Hury Viridiana Hernández-Galdámez, Carolina Piña-Vázquez, Tania Araujo-Ramos and Indrabahadur Singh EP300 as a Molecular Integrator of Fibrotic Transcriptional Programs cancer Abstract: Fibrosisis a condition characterized by the excessive accumulation of extra cellular matrix proteins in tissues, leading to organ dysfunction and failure. Recen tstudies have identi?ed EP300 ,a histone acetyltransferase, […]
Therapeutic targeting of splicing variants in cancer
Pouya Sarvari, Karla Rubio, Stephanie Dobersch, Aglaia Ntokou, and Verónica Vallejo-Ruiz Therapeutic targeting of splicin gvariants in cancer Abstract The cellular process of removing introns from pre-mRNAs and connecting the remaining exons to produce a mature mRNA is termed mRNA splicing. However, exons from the same pre-mRNA can be joined indifferent combinations by AlternativeSplicing(AS), generating […]
Pulmonary Aspergillosis in Pediatric Patient
Coral-García Miguel Ángel, Serrano-Guevara Christian Mauricio, León-López Magdalena, López-Santos Héctor Alfonso, Barbosa-Contreras Meylin, Maldonado-Castañeda Sandra, Rubio-Nava Karla María, Guevara-Navarrete César Martín, Silva-Campos Irlanda Mariel and Yaneth Martínez Tovilla* Pulmonary Aspergillosis in Pediatric Patient Abstract Introduction:Aspergillusis a branched septate filamentous fungus that can induce lethal and invasive infections in patients suffering from autoimmune or inflammatory diseases, […]
Environmental Epigenetics and Obesity
Ramirez-Diaz Ivonne, Lobato Sagrario, Perez-Gonzalez Andrea, Morales Alejandra and Rubio Karla Environmental Epigenetics and Obesity AbstractIn recent years, increasing interest on the effects of dietary components onepigenetic processes and, consequently, on the regulation of gene expression andmetabolic responses has led clinical efforts worldwide to approach obesity. Wheninadequate, food consumption leads to chronic and non-communicable diseases(CNCD) […]
Nutriepigenómica en el estrés oxidativo asociado a contaminación
Karla Rubio, Estefani Y. Hernández-Cruz, Diana G. Rogel-Ayala, Pouya Sarvari, Ciro Isidoro, Guillermo Barreto and José Pedraza-Chaverri Nutriepigenomics in Environmental-Associated Oxidative Stress. Complex molecular mechanisms define our responses to environmental stimuli. Beyond the DNA sequence itself, epigenetic machinery orchestrates changes in gene expression induced by diet, physical activity, stress and pollution, among others. Importantly, nutrition […]
El posicionamiento de los nucleosomas que contienen γ-H2AX precede a la desmetilación activa del ADN y al inicio de la transcripción
Stephanie Dobersch, Karla Rubio, Indrabahadur Singh, Stefan Günther, Johannes Graumann, Julio Cordero, Rafael Castillo-Negrete, Minh Bao Huynh, Aditi Mehta 2, Peter Braubach, Hector Cabrera-Fuentes, Jürgen Bernhagen, Cho-Ming Chao, Saverio Bellusci, Andreas Günther, Klaus T Preissner, Sita Kugel, Gergana Dobreva, Malgorzata Wygrecka, Thomas Braun, Dulce Papy-Garcia, Guillermo Barreto 16 feb 2021 Position of first nucleosome containing […]
